Bokamoso ba Phekolo ea Psychedelic ke Eng?

Puisano e latelang le neuropharmacologist le rakhemisi Cody Wenthur e bua ka tse ling tsa liphetoho tsa kalafo ea psychedelic le sechabeng sa sejoale-joale. Lab ea lipatlisiso tsa Dr. Wenthur e nehetsoe mekhoeng e mengata e fapaneng, ea phetolelo e reretsoeng ho ntlafatsa kalafo ea mafu a kelello, haholoholo mathata a ts'ebeliso ea lithethefatsi le khatello e kholo ea khatello ea maikutlo.

Ka 2021, re hara seo bahlalosi ba bang ba se bitsang "nchafatso ea psychedelic." Taba ea mantlha, u kena kae ka nako ea hajoale?

Hajoale ke mofuputsi ea ka sehloohong le motlatsi oa moprofesa Univesithing ea Wisconsin, moo ke bileng lehlohonolo le lekaneng ho kenela sehlopha se seholo, se tsoang litsing tse fapaneng, sa bo-ramahlale le barutehi ba ikakhetseng ka setotsoana thutong ea psychedelics. Tsebo e fumanehang sehlopheng sena e fapana ho tloha tlholehong ho ea ho ea kelello, ho tloha nalaneng ho ea ho e fetelletseng, empa karolo ea ka ea ho etsa lipatlisiso e shebile ho hokela litlamorao tsa limolek'hule le litlamorao tse sebetsang tsa boits'oaro.

Hammoho le boiteko bona ba ho etsa lipatlisiso, ke boetse ke thabile haholo ho qala ho ba mookameli oa khetho ea Master's degree ho Patlisiso ea Psychoactive Pharmaceutical, e tla qala sehlopha sa eona sa pele ho Fall 2021.

Mosebetsi oa hau o joang hona joale mme o leka ho ntlafatsa bophelo bo botle ba kelello joang?

Ho qala ka koetliso ea ka ea pele-pele ea bongaka le ea mahlale ho fihlela kajeno, litabatabelo tsa ka tsa lipatlisiso esale li shebile ho utloisisa hore na liketso tsa limolek'hule tse nyane tsa kelello li ka lebisa joang liphetohong tse tebileng, tsa nako e telele tsa boits'oaro. Ka bomalimabe, e meng ea mehlala ea rona e totobetseng ea ketsahalo ena, joalo ka nts'etsopele ea mathata a ts'ebeliso ea lithethefatsi, e senya bophelo ba kelello le ba 'mele ka tsela e makatsang. Ka hona, merero ea ka e meholo ea laboratori e shebane le ho nts'etsapele mekhoa e ka fokotsang kapa ea etsolla litlamorao tsa boits'oaro bo kotsi bo ithutoang le ba tloaelo.

Ka lehlakoreng le leng, hona ho kenyelletsa ts'ebeliso le nts'etsopele ea mekhoa ea "ente" e thibelang limolek'hule tse nyane tsa psychoactive ho kenella lipheo tsa tsona bokong, ka lehlakoreng le leng, ho kenyelletsa tšebeliso ea metsoako e joalo ka li-psychedelics tse bonahalang li bula fensetere ea polasetiki ea methapo.

Ha re nahana ka li-psychedelics ka kotloloho, hajoale re sebelisa lithuto tsa pele ho kalafo le tsa batho ho utloisisa hore na litlamorao tsa mmele, joalo ka ho lokolloa ha cortisol, le litlamorao tsa kelello, joalo ka pono e fetotsoeng le moelelo, li nka bohato ba ho fetola boholo le bolelele ba nako e susumetsoang ke psychedelic. liphetoho tsa boitšoaro. Joaloka motho eo kenyelletso ea hae ho mahlale a laboratori a fetang lipatlisisong tsa lets'oao la serotonin pele a tsoela pele ho hlahisa litlamorao ho ithuteng, ke ntse ke tsoela pele ho ba le tjantjello e kholo ho merero ea rona e tsoelang pele e shebileng hore na mekhahlelo ea ho sebetsana le li-anti-depressing ka potlako e tsoang lihlopheng tse fapaneng ka ho felletseng, joalo ka joalo ka psilocybin le ketamine, li ka kopana kapa tsa kopana.

Saense ea Psychedelic le bongaka li bonahala li tsoela pele ka bongata. U shebile eng haufi-ufi?

Ho na le lintlafatso tse etsahalang ka har'a boto, empa ke khahliloe haholo ke lithuto tse lekolang liphapano le litlamorao tsa liphihlelo tse hlakileng tse fetotsoeng khahlanong le litlamorao tsa limolek'hule tse khothaletsoang ke metsoako ea psychedelic. Tsoelo-pele ea morao-rao ea ho khetholla li-analogue tsa psychedelic tse khothalletsang polasetiki ea methapo ea kutlo, empa li sa bonahale li baka maemo a fetotsoeng a temoho, ho bonahala e kanna ea fella ka lisebelisoa tse bohlokoa haholo tsa ho sebetsana le hore na ho ba le mefuta e itseng ea lintho tse makatsang ho bohlokoa ho ts'ehetsa phetoho ea nako e telele.

Ke boetse ke lula ke na le tjantjello ea ho latela mokhoa oa psychedelic-assisted psychotherapy o susumetsang mekhoa e meng e kopanyang ho kenella ha methapo ea pelo le liphekolo tse netefalitsoeng e seng tsa pharmacologic tse fanang ka maano a ntlafetseng a ts'ebeliso ea kelello. Ha li-psychotherapies tse thusitsoeng ke psychedelic li ntse li tsoela pele ho hlahlojoa ka mekhahlelo e mengata le ho feta ea maloetse a kelello, ka mokhoa o ts'oanang e tla ba ho khahlisang ho bona hore na mokhoa ona ka kakaretso o na le molemo o pharaletseng, haholo hobane o ka ts'ehetsa ts'ebeliso ea ona e le lisebelisoa tsa mahlale a methapo e ka thusa ho tsebisa nts'etsopele ea mekhoa e meng e sebetsanang le phumano ea 'mele le tlhokomelo e ntlafalitsoeng ea tlhokomelo ea bophelo ba kelello.

A mang a mathata kapa liphephetso tsa hajoale saenseng ea bongaka le bongaka ke afe?

Sehlopha sa basebetsi ba psychedelics ho UW-Madison le nna re fane ka maikutlo a mangata a morao tjena ho potso ena hantle ha re ntse re sebetsana le hore na lenaneo la mong'a rona e mocha le ka fihlela litlhoko tse tsoelang pele tsa tšimo joang.

Qholotso e 'ngoe ea bohlokoahali eo re e fumaneng kapele ke ho netefatsa hore mahlale a psychedelic a boloka boemo bo phahameng ka ho fetisisa ba ho ba le boits'oaro le bots'epehi ho pholletsa le karolo ea ona ea kholo ea joale. Ha tšimo e atoloha ho feta maemo a lipatlisiso tsa thuto ho indasteri e pharaletseng ea meriana, ho tla ba le tlhoko e tsoelang pele ea bafuputsi ba koetliselitsoeng ho utloisisa mohopolo o ikhethang oa mahlale, taolo, setso le setso le boits'oaro bo hlokahalang ho etsa lithuto tsa boleng bo holimo sebakeng sena. .

Mohlala o le mong o amehang hang-hang, barupeluoa ba bacha tšimong ba hloka ho ba le kutloisiso e tebileng ea hore na litlamorao tse ntlafalitsoeng tsa psychedelic li ka ama moralo oa liteko joang, haholoholo ha litebello tse fetotsoeng tsa barupeluoa ba liteko tsa bongaka li ka hlaha ho latela litlaleho tsa "tse e-so ka li bonoa. "litlamorao tse kenang tlhokomelong ea sechaba.

Qholotso e 'ngoe e kholo ke mosebetsi oa lefapha la mahlale le boits'oaro ba ho eketsa ho tsepamisa maikutlo litabeng tsa nalane le tsa setso sa hajoale tse potolohileng phapano, tekano le ho kenyeletsoa sebakeng sa lipatlisiso tsa meriana. Lithuto tsa kelello tse thusitsoeng ke psychedelic ho fihlela joale ha li so ka li emela palo e pharalletseng ea batho ba Amerika, mme menehelo ea bafuputsi, litsebi le batsamaisi ba tsebo ea setso e tsoang metseng e sa emeloang hangata e fokotsoe.

Ho fana ka mohlala o mong oa kamoo kameho ena e pharalletseng e sebetsang hanghang lebaleng ka kakaretso, kaha boits'oaro bo ka kopana le menahano ea bankakarolo le ho amohela maemo a kalafo, khaello ena ea phapano le ho se khone ho lekanya litlamorao tsa eona ka kotlolloho ea liprothokhole tse sa lekanang tse ka sebelisoang ka botlalo bakeng sa ts'ebeliso ea kliniki e pharalletseng le e nang le toka maemong a tumello ea molao.

Ho sebetsana le phephetso ena, ke lumela hore tšimo e hloka ho eketsoa ha thuto le tlhokomeliso ea litaba tsena, ho ba le seabo se eketsehileng le balekane ba sechaba le ho tsepamisa maikutlo lithutong tsa tekatekano ea bophelo bo botle, le menyetla e tsepamisitseng maikutlo e khothalletsang ho kena le katleho ea bafuputsi ka bomong ba hlahisitseng semelo se fapaneng, le manane a rona a lipatlisiso le tsa thuto a ntse a sebeletsa ho ts'ehetsa tšehetso ho e ngoe le e ngoe ea lintlha tsena.

Ke leboha nako ea hau haholo, Cody!